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Sotalol hydrochloride 40mg, 160mg
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Symptomatic and treatment requiring supraventricular tachycardiac arrhythmia
Severe symptomatic ventricular tachycardiac arrythmia
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The initial-therapy with Rentibloc 40 : 2-3 x 40mg / day
The maintenance-therapy with Rentibloc 160 : up to 3 x 160mg / day
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The most important adverse effects are torsade de pointes and other serious new ventricular arrhythmias, occurring at rates almost 4% and 1%, respectively, in the VT/VF population.
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Rentibloc tab. is contraindicated in patients with bronchial asthma, sinus bradycardia, second and thied degree AV block, unless a functional pacemaker is present, congenital or acquired long QT syndromes, cardiogenic shock, uncontrolled congestive heart failure, and previous evidence of hypersensitivity to Rentibloc.
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Renal impairment : sotalol hydrochloride is mainly eliminated via the kidneys through glomerular filtration and to a small degree by tubular secretion. There is a direct relationship between renal function, as measured by serum creatinine or creatinine clearance, and the elimination rate of sotalol.
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